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Body Sculpting Method Proves Efficient and Effective

Ice-slurry injection is a novel method for subcutaneous body fat reduction.

By Emilee Green | Jun 22, 2022

Wausau, WI (June 22, 2022) – Cryolipolysis uses tissue cooling to solidify lipids, preferentially damaging lipid-rich cells. Commonly known as “fat freezing,” cryolipolysis via a non-invasive applicator has become a popular method for body sculpting. Cryolipolysis with injectable ice-slurry will soon become an efficient, effective and customizable method of body sculpting. This study used modeling to determine the dosimetry for injectable ice-slurry treatments and demonstrated the important role that the physical properties of the slurry and the composition of target adipose tissue can play in treatment outcomes.  

Drs. Lilit Garibyan & Peiyun NiThe basic science report, led by Lilit Garibyan, MD, PhD and Peiyun Ni, MD, is titled, “Total ice content and lipid saturation determine adipose tissue cryolipolysis by injection of ice-slurry.” The report, published in Lasers in Surgery and Medicine (LSM), the official journal of the American Society for Laser Medicine and Surgery, Inc. (ASLMS), was selected as the June 2022 Editor’s Choice.

“We had already demonstrated that ice-slurry injection is a novel method for efficient and effective subcutaneous adipose tissue reduction,” said Garibyan. “We did the current study to better understand the heat exchange and phase changes that occur after ice-slurry injection into subcutaneous tissue. This work is important as it helps determine the important parameters of ice-slurry and adipose tissue that influence the amount of fat reduction with this treatment.”

Dr. Peiyun Ni is a resident in Internal Medicine at Massachusetts General Hospital. Dr. Lilit Garibyan is a physician-scientist and board-certified dermatologist with appointments as an Assistant Professor of Dermatology at Harvard Medical School and a Physician-Scientist at the Wellman Center for Photomedicine at Massachusetts General Hospital. Dr. Garibyan is the co-inventor of the injectable ice-slurry technology.

Editor’s Choice is an exclusive article published in LSM, the official journal of the ASLMS. View the complete manuscript.

The American Society for Laser Medicine and Surgery, Inc. (ASLMS) is the largest multidisciplinary professional organization dedicated to the development and application of lasers and related technology for health care applications. ASLMS promotes excellence in patient care by advancing biomedical application of lasers and other related technologies worldwide. ASLMS membership includes physicians, surgeons, nurses, and allied health professionals representing multiple specialties, physicists involved in product development, biomedical engineers, biologists, industry representatives and manufacturers. For more information, visit


The American Society for Laser Medicine and Surgery, Inc. is the world’s largest scientific organization dedicated to promoting research, education and high standards of clinical care in the field of medical laser applications. It provides a forum for the exchange of scientific information and participation in communicating the latest developments in laser medicine and surgery to clinicians, research investigators, government and regulatory agencies, and the public.

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