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More Efficient Scar Prevention

Laser exposure specifically targeting the early phases of wound healing may be the key to scar minimization.

By Stephanie Grauden | Jan 23, 2018

lsm-17-0060-karmisholt-editedWausau, WI (January 23, 2018) – Laser treatment in the early phases of wound healing may reduce scar formation. However, little is known on the appropriate timing and fluence levels of laser exposure to maximize benefits. In a recent study published in Lasers in Surgery and Medicine (LSM), the official journal of the American Society for Laser Medicine and Surgery, Inc. (ASLMS), the clinical and histologic effect of non-ablative-fractional erbium-glass 1,540nm laser at three early time points at a range of fluence levels (30-70mJ) is investigated.

The research was conducted by Katrine E. Karmisholt, MD; Emily Wenande, MD; Daniel Thaysen‐Petersen, MD; Peter A. Philipsen, MsScEE, PhD; Uwe Paasch, MD, PhD; and Merete Haedersdal, MD. Their manuscript titled, “Early Intervention with Non-Ablative Fractional Laser to Optimize Cutaneous Scarring – A Randomized Controlled Trial on the Impact of Intervention Time and Fluence Level” was selected as Editor’s Choice in the January 2018 issue of LSM.

“A single non-ablative fractional laser exposure performed in the early wound healing phases may optimize scar formation,” said Dr. Karmisholt.

At all fluence levels tested, a single laser treatment applied one day before, immediately after, or two weeks after wounding induced improvement compared to untreated controls, in both Patient-Observer-Scar-Assessment-Scale as well as in maturity and quality of collagen on histology.

Editor’s Choice is an exclusive article published in LSM, the official journal of the ASLMS. View the complete manuscript.

The American Society for Laser Medicine and Surgery, Inc. (ASLMS) is the largest multi-disciplinary professional organization, dedicated to the development and application of lasers and related technology for health care applications. ASLMS promotes excellence in patient care by advancing biomedical application of lasers and other related technologies worldwide. Currently, ASLMS has over 4,000 members, including physicians and surgeons representing more than 51 specialties, physicists involved in product development, biomedical engineers, biologists, nurses, industry representatives and manufacturers. For more information, visit

The American Society for Laser Medicine and Surgery is the world’s largest scientific organization dedicated to promoting research, education and high standards of clinical care in the field of medical laser applications. It provides a forum for the exchange of scientific information and participation in communicating the latest developments in laser medicine and surgery to clinicians, research investigators, government and regulatory agencies, and the public.

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